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Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule
Fibroblast growth factor-23 (FGF23), a hormone central to phosphate and vitamin D metabolism, reduces renal absorption of phosphate by downregulating the sodium-phosphate cotransporter Npt2a. However, the mechanisms of FGF23 action in the kidney are unclear, as Npt2a localizes to the proximal tubule...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Nephrology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060419/ https://ncbi.nlm.nih.gov/pubmed/19357251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008070783 |
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