Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis

Retinal pigment epithelial cells (RPE) expresses two transport systems (SOPT1 and SOPT2) for oligopeptides. Hepcidin is an iron-regulatory peptide hormone consisting of 25 amino acids. This hormone binds to ferroportin, an iron exporter expressed on the cell surface, and facilitates its degradation....

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Autores principales: Chothe, Paresh P., Gnana-Prakasam, Jaya P., Ananth, Sudha, Martin, Pamela M., Kannan, Ram, Hinton, David R., Smith, Sylvia B., Ganapathy, Vadivel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060409/
https://ncbi.nlm.nih.gov/pubmed/21219868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.01.018
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