Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis

Retinal pigment epithelial cells (RPE) expresses two transport systems (SOPT1 and SOPT2) for oligopeptides. Hepcidin is an iron-regulatory peptide hormone consisting of 25 amino acids. This hormone binds to ferroportin, an iron exporter expressed on the cell surface, and facilitates its degradation....

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Main Authors: Chothe, Paresh P., Gnana-Prakasam, Jaya P., Ananth, Sudha, Martin, Pamela M., Kannan, Ram, Hinton, David R., Smith, Sylvia B., Ganapathy, Vadivel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060409/
https://ncbi.nlm.nih.gov/pubmed/21219868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.01.018
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