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Morphogenesis and maintenance of the 3D-thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium

Expansion of thymic epithelial cysts represents disruption of an organized three-dimensional (3D) thymic epithelial cell (TEC) meshwork, which is crucial for T-lymphocyte development. Although the FoxN1-null mutant develops a rudimentary 2D-cystic thymus, 2D-thymic cyst-lining resulting from a dGUO...

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Detalhes bibliográficos
Main Authors: Guo, Jianfei, Rahman, Moshiur, Cheng, Lili, Zhang, Shuangmin, Tvinnereim, Amy, Su, Dong-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060403/
https://ncbi.nlm.nih.gov/pubmed/21109991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-010-0700-8
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