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Role of an extracellular loop in determining the stoichiometry of Na(+)–HCO(3)(−) cotransporters

The Na(+)–HCO(3)(−) cotransporters (NBCs) of the solute carrier 4 family (SLC4) are critical for regulating pH in cells as well as in fluids such as blood and cerebrospinal fluid. Moreover, mutations and gene disruptions in NBC are linked to a wide range of pathologies. NBCe1 (SLC4A4) is electrogeni...

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Autori principali: Chen, Li-Ming, Liu, Ying, Boron, Walter F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060367/
https://ncbi.nlm.nih.gov/pubmed/21224233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.198713
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