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Relief of autoinhibition of the electrogenic Na-HCO(3) cotransporter NBCe1-B: role of IRBIT vs. amino-terminal truncation
Two maneuvers known to stimulate electrogenic sodium bicarbonate cotransporter 1 (NBCe1) activity are 1) deletion from the cytosolic amino-terminus (Nt) of NBCe1-C of an 87-amino acid sequence that contains an autoinhibitory domain (AID); and 2) binding of the protein IRBIT to elements within the sa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287159/ https://ncbi.nlm.nih.gov/pubmed/22012331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00352.2011 |
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