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Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
Ozonide OZ439 is a synthetic peroxide antimalarial drug candidate designed to provide a single-dose oral cure in humans. OZ439 has successfully completed Phase I clinical trials, where it was shown to be safe at doses up to 1,600 mg and is currently undergoing Phase IIa trials in malaria patients. H...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060245/ https://ncbi.nlm.nih.gov/pubmed/21300861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015762108 |
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