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Expanded CAG/CTG Repeat DNA Induces a Checkpoint Response That Impacts Cell Proliferation in Saccharomyces cerevisiae
Repetitive DNA elements are mutational hotspots in the genome, and their instability is linked to various neurological disorders and cancers. Although it is known that expanded trinucleotide repeats can interfere with DNA replication and repair, the cellular response to these events has not been cha...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
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Public Library of Science
2011
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060079/ https://ncbi.nlm.nih.gov/pubmed/21437275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001339 |
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