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Sensing of Replication Stress and Mec1 Activation Act through Two Independent Pathways Involving the 9-1-1 Complex and DNA Polymerase ε

Following DNA damage or replication stress, budding yeast cells activate the Rad53 checkpoint kinase, promoting genome stability in these challenging conditions. The DNA damage and replication checkpoint pathways are partially overlapping, sharing several factors, but are also differentiated at vari...

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מידע ביבליוגרפי
Main Authors: Puddu, Fabio, Piergiovanni, Gabriele, Plevani, Paolo, Muzi-Falconi, Marco
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060063/
https://ncbi.nlm.nih.gov/pubmed/21436894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002022
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