Phosphorylation of the Budding Yeast 9-1-1 Complex Is Required for Dpb11 Function in the Full Activation of the UV-Induced DNA Damage Checkpoint

Following genotoxic insults, eukaryotic cells trigger a signal transduction cascade known as the DNA damage checkpoint response, which involves the loading onto DNA of an apical kinase and several downstream factors. Chromatin modifications play an important role in recruiting checkpoint proteins. I...

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Detalhes bibliográficos
Main Authors: Puddu, Fabio, Granata, Magda, Di Nola, Lisa, Balestrini, Alessia, Piergiovanni, Gabriele, Lazzaro, Federico, Giannattasio, Michele, Plevani, Paolo, Muzi-Falconi, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493362/
https://ncbi.nlm.nih.gov/pubmed/18541674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00330-08
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