Phosphorylation of the Budding Yeast 9-1-1 Complex Is Required for Dpb11 Function in the Full Activation of the UV-Induced DNA Damage Checkpoint

Following genotoxic insults, eukaryotic cells trigger a signal transduction cascade known as the DNA damage checkpoint response, which involves the loading onto DNA of an apical kinase and several downstream factors. Chromatin modifications play an important role in recruiting checkpoint proteins. I...

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Main Authors: Puddu, Fabio, Granata, Magda, Di Nola, Lisa, Balestrini, Alessia, Piergiovanni, Gabriele, Lazzaro, Federico, Giannattasio, Michele, Plevani, Paolo, Muzi-Falconi, Marco
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493362/
https://ncbi.nlm.nih.gov/pubmed/18541674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00330-08
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