Profound Desensitization by Ambient GABA Limits Activation of δ-Containing GABA(A) Receptors during Spillover

High-affinity extrasynaptic GABA(A) receptors (GABA(A)Rs) are a prominent feature of cerebellar granule neurons and thalamic relay neurons. In both cell types, the presence of synaptic glomeruli would be expected to promote activation of these GABA(A)Rs, contributing to phasic spillover-mediated cur...

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Detalhes bibliográficos
Main Authors: Bright, Damian P., Renzi, Massimiliano, Bartram, Julian, McGee, Thomas P., MacKenzie, Georgina, Hosie, Alastair M., Farrant, Mark, Brickley, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059572/
https://ncbi.nlm.nih.gov/pubmed/21228184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2996-10.2011
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