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Intrinsic IL-21 signaling is critical for CD8 T cell survival and memory formation in response to vaccinia viral infection

CD4 T cell help plays an important role in promoting CD8 T cell immunity to pathogens. In models of infection with vaccinia virus (VV) and Listeria monocytogenes, CD4 T cell help is critical for the survival of activated CD8 T cells during both the primary and memory recall responses. Still unclear,...

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Библиографические подробности
Главные авторы: Novy, Patricia, Huang, Xiaopei, Leonard, Warren J., Yang, Yiping
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059504/
https://ncbi.nlm.nih.gov/pubmed/21257966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003009
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