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Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA
Plasmacytoid dendritic cells (pDCs) play a critical role in antiviral immunity through their ability to produce large amounts of type I IFNs. Activation of pDCs upon viral infection has been shown to be dependent on MyD88 and mediated by Toll-like receptors (TLR) 7 and 9, which sense viral ssRNA and...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851984/ https://ncbi.nlm.nih.gov/pubmed/20308556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913291107 |
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