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A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

Recent advances have suggested a crucial role of the innate immunity in shaping adaptive immune responses. How activation of innate immunity promotes adaptive T-cell responses to pathogens in vivo is not fully understood. It has been thought that Toll-like receptor (TLR)–mediated control of adaptive...

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Detalhes bibliográficos
Main Authors: Quigley, Michael, Martinez, Jennifer, Huang, Xiaopei, Yang, Yiping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652371/
https://ncbi.nlm.nih.gov/pubmed/18948575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-148809
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