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The Adaptor Molecule MyD88 Directly Promotes CD8 T cell Responses to Vaccinia Virus

Vaccinia Virus (VACV) elicits a robust CD8 T cell response that plays an important role in host resistance. To date, there is little information on the molecules that are essential to generate large pools of VACV-specific effector CD8 T cells. Here, we show that the adaptor molecule MyD88 is critica...

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Detalhes bibliográficos
Main Authors: Zhao, Yuan, Trez, Carl De, Flynn, Rachel, Ware, Carl F., Croft, Michael, Salek-Ardakani, Shahram
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712123/
https://ncbi.nlm.nih.gov/pubmed/19414781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803682
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