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A Phase I Study of Continuous Infusion Cilengitide in Patients with Solid Tumors
BACKGROUND: Cilengitide (EMD121974) is a cyclized pentapeptide that is a potent and selective integrin antagonist which has shown activity in malignant gliomas. In all previous studies, cilengitide has been administered in an intermittent fashion. However, cilengitide has a short half-life of 3-5 ho...
שמור ב:
| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059335/ https://ncbi.nlm.nih.gov/pubmed/20839028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9537-9 |
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