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Prostaglandin E(2) Signals Through PTGER2 to Regulate Sclerostin Expression
The Wnt signaling pathway is a robust regulator of skeletal homeostasis. Gain-of-function mutations promote high bone mass, whereas loss of Lrp5 or Lrp6 co-receptors decrease bone mass. Similarly, mutations in antagonists of Wnt signaling influence skeletal integrity, in an inverse relation to Lrp r...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059227/ https://ncbi.nlm.nih.gov/pubmed/21436889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017772 |
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