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The synthesis of protected 5'-mercapto-2',5'-dideoxyribonucleoside-3'-O-phosphoramidites; uses of 5'-mercapto-oligodeoxyribonucleotides.

The syntheses of the four novel, base protected 5'-(S-triphenylmethyl)mercapto-2',5'-dideoxyribonucleoside-3 '-O-(2-cyanoethyl N,N-diisopropylphosphoramidites) are described. These compounds have been used to prepare 5'-(S-triphenylmethyl) mercapto-oligodeoxyribonucleotides, which are readily purifi...

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Publicat a:Nucleic Acids Res
Autors principals: Sproat, B S, Beijer, B, Rider, P, Neuner, P
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1987
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3601657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.12.4837
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