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Highly efficient oligodeoxyribonucleotide synthesis using fully base protected phosphodiester building blocks carrying 2-(1-methylimidazol-2-yl) phenyl protection of the phosphate.
Four fully base protected phosphodiester building blocks have been synthesised and fully characterised. The phosphate protecting group used was the 2-(1-methylimidazol-2-yl)phenyl group, enabling intramolecular catalysis of the condensation step in oligodeoxyribonucleotide synthesis by the solid pha...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1986
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC339575/ https://ncbi.nlm.nih.gov/pubmed/3951997 |
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