Alternative splicing of Caspase 9 is modulated by the PI3K/Akt pathway via phosphorylation of SRp30a

Increasing evidence points to the functional importance of alternative splice variations in cancer pathophysiology. Two splice variants are derived from the CASP9 gene via the inclusion (Casp9a) or exclusion (Casp9b) of a four exon cassette. Here we show that alternative splicing of Casp9 is dysregu...

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Detalhes bibliográficos
Main Authors: Shultz, Jacqueline C., Goehe, Rachel W., Wijesinghe, D. Shanaka, Murudkar, Charuta, Hawkins, Amy J., Shay, Jerry W., Minna, John D., Chalfant, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059118/
https://ncbi.nlm.nih.gov/pubmed/21045158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1545
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