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Ceramide-Activated Protein Phosphatase (CAPP) involvement in insulin resistance via Akt, SRp40, and RNA splicing in L6 skeletal muscle cells

Elevated TNFα levels are associated with insulin resistance, but the molecular mechanisms linking cytokine signaling to impaired insulin function remain elusive. We previously demonstrated a role for Akt in insulin regulation of PKCβII alternative splicing through phosphorylation of SRp40, a require...

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Detalhes bibliográficos
Main Authors: Ghosh, Nilanjan, Patel, Niketa, Jiang, Kun, Watson, James E., Cheng, Jin, Chalfant, Charles E., Cooper, Denise R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664306/
https://ncbi.nlm.nih.gov/pubmed/17158207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-0750
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