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Regulation of Tat Acetylation and Transactivation Activity by the Microtubule-associated Deacetylase HDAC6
Reversible acetylation of Tat is critical for its transactivation activity toward HIV-1 transcription. However, the enzymes involved in the acetylation/deacetylation cycles have not been fully characterized. In this study, by yeast two-hybrid assay, we have discovered the histone deacetylase HDAC6 t...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059013/ https://ncbi.nlm.nih.gov/pubmed/21220424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208884 |
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