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Regulation of Human Mitochondrial Aldehyde Dehydrogenase (ALDH-2) Activity by Electrophiles in Vitro

Recently, mitochondrial aldehyde dehydrogenase (ALDH-2) was reported to reduce ischemic damage in an experimental myocardial infarction model. ALDH-2 activity is redox-sensitive. Therefore, we here compared effects of various electrophiles (organic nitrates, reactive fatty acid metabolites, or oxida...

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Detalhes bibliográficos
Main Authors: Oelze, Matthias, Knorr, Maike, Schell, Richard, Kamuf, Jens, Pautz, Andrea, Art, Julia, Wenzel, Philip, Münzel, Thomas, Kleinert, Hartmut, Daiber, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058968/
https://ncbi.nlm.nih.gov/pubmed/21252222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190017
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