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Prolonged Mechanical Stretch is Associated with Upregulation of Hypoxia-Inducible Factors and Reduced Contraction in Rat Inferior Vena Cava

BACKGROUND: Decreased venous tone and vein wall dilation may contribute to varicose vein formation. We have shown that prolonged vein wall stretch is associated with upregulation of matrix metalloproteases (MMPs) and decreased contraction. Because hypoxia-inducible factors (HIFs) expression also inc...

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Detaylı Bibliyografya
Asıl Yazarlar: Lim, Chung S., Qiao, Xiaoying, Reslan, Ossama M., Xia, Yin, Raffetto, Joseph D., Paleolog, Ewa, Davies, Alun H., Khalil, Raouf A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058747/
https://ncbi.nlm.nih.gov/pubmed/21106323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2010.09.018
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