Prolonged Mechanical Stretch is Associated with Upregulation of Hypoxia-Inducible Factors and Reduced Contraction in Rat Inferior Vena Cava

BACKGROUND: Decreased venous tone and vein wall dilation may contribute to varicose vein formation. We have shown that prolonged vein wall stretch is associated with upregulation of matrix metalloproteases (MMPs) and decreased contraction. Because hypoxia-inducible factors (HIFs) expression also inc...

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Autores principales: Lim, Chung S., Qiao, Xiaoying, Reslan, Ossama M., Xia, Yin, Raffetto, Joseph D., Paleolog, Ewa, Davies, Alun H., Khalil, Raouf A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058747/
https://ncbi.nlm.nih.gov/pubmed/21106323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2010.09.018
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