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Prolonged Increases in Vein Wall Tension Increase Matrix Metalloproteinases and Decrease Constriction in Rat Vena Cava. Potential Implications in Varicose Veins
BACKGROUND: Increased venous hydrostatic pressure plays a role in the pathogenesis of varicose veins. Increased expression of matrix metalloproteinases (MMPs) has been identified in varicose veins. Also, we have shown that MMP-2 inhibits venous contraction. However, the relation between venous press...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575039/ https://ncbi.nlm.nih.gov/pubmed/18502086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2008.03.004 |
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