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Prolonged Increases in Vein Wall Tension Increase Matrix Metalloproteinases and Decrease Constriction in Rat Vena Cava. Potential Implications in Varicose Veins

BACKGROUND: Increased venous hydrostatic pressure plays a role in the pathogenesis of varicose veins. Increased expression of matrix metalloproteinases (MMPs) has been identified in varicose veins. Also, we have shown that MMP-2 inhibits venous contraction. However, the relation between venous press...

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Autors principals: Raffetto, Joseph D., Qiao, Xiaoying, Koledova, Vera V., Khalil, Raouf A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575039/
https://ncbi.nlm.nih.gov/pubmed/18502086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2008.03.004
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