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Matrix Metalloproteinase-2 Induced Venous Dilation via Hyperpolarization and Activation of K(+) Channels. Relevance to Varicose Vein Formation
BACKGROUND: Varicose veins are a common disorder of extensive venous dilation and remodeling with as yet unclear mechanism. Studies have shown elevated plasma and tissue levels of matrix metalloproteinases (MMPs) in human varicose veins and animal models of venous hypertension. Although the effects...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1794684/ https://ncbi.nlm.nih.gov/pubmed/17264019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2006.10.041 |
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