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Selective Killing of Tumor Neo-Vasculature Paradoxically Improves Chemotherapy Delivery to Tumors

Anti-angiogenic therapies are frequently used with concomitantly administered cancer chemotherapy to improve outcomes, but the mechanism for the benefit of the combination is uncertain. We describe a mechanism by which a specific, cytotoxic anti-vascular agent causes vascular remodeling and improved...

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Bibliografiske detaljer
Main Authors: Escorcia, Freddy E., Henke, Erik, McDevitt, Michael R., Villa, Carlos H., Smith-Jones, Peter, Blasberg, Ronald G., Benezra, Robert, Scheinberg, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058681/
https://ncbi.nlm.nih.gov/pubmed/21045141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2029
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