Selective Alpha-Particle Mediated Depletion of Tumor Vasculature with Vascular Normalization

BACKGROUND: Abnormal regulation of angiogenesis in tumors results in the formation of vessels that are necessary for tumor growth, but compromised in structure and function. Abnormal tumor vasculature impairs oxygen and drug delivery and results in radiotherapy and chemotherapy resistance, respectiv...

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Detalhes bibliográficos
Main Authors: Jaggi, Jaspreet Singh, Henke, Erik, Seshan, Surya V., Kappel, Barry J., Chattopadhyay, Debjit, May, Chad, McDevitt, Michael R., Nolan, Daniel, Mittal, Vivek, Benezra, Robert, Scheinberg, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801076/
https://ncbi.nlm.nih.gov/pubmed/17342201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000267
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