Selective Alpha-Particle Mediated Depletion of Tumor Vasculature with Vascular Normalization

BACKGROUND: Abnormal regulation of angiogenesis in tumors results in the formation of vessels that are necessary for tumor growth, but compromised in structure and function. Abnormal tumor vasculature impairs oxygen and drug delivery and results in radiotherapy and chemotherapy resistance, respectiv...

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Hlavní autoři: Jaggi, Jaspreet Singh, Henke, Erik, Seshan, Surya V., Kappel, Barry J., Chattopadhyay, Debjit, May, Chad, McDevitt, Michael R., Nolan, Daniel, Mittal, Vivek, Benezra, Robert, Scheinberg, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801076/
https://ncbi.nlm.nih.gov/pubmed/17342201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000267
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