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Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes

Single wall carbon nanotube (SWCNT) constructs were covalently appended with radiometal-ion chelates (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid [DOTA] or desferrioxamine B [DFO]) and the tumor neovascular-targeting antibody E4G10. The E4G10 antibody specifically targeted the monomeric...

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Detalhes bibliográficos
Main Authors: Ruggiero, Alessandro, Villa, Carlos H, Holland, Jason P, Sprinkle, Shanna R, May, Chad, Lewis, Jason S, Scheinberg, David A, McDevitt, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962274/
https://ncbi.nlm.nih.gov/pubmed/21042424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S13300
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