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A THERAPEUTIC OX40 AGONIST DYNAMICALLY ALTERS DENDRITIC, ENDOTHELIAL AND T CELL SUBSETS WITHIN THE ESTABLISHED TUMOR MICROENVIRONMENT

Little preclinical modeling currently exists to support the use of OX40 agonists as therapeutic agents in the setting of advanced cancers, as well as, the mechanisms through which therapeutic efficacy is achieved. We demonstrate that treatment of mice bearing well-established day 17 sarcomas with a...

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Bibliographische Detailangaben
Hauptverfasser: Pardee, Angela D., McCurry, Dustin, Alber, Sean, Hu, Peisheng, Epstein, Alan L., Storkus, Walter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058673/
https://ncbi.nlm.nih.gov/pubmed/21045144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1369
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