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A THERAPEUTIC OX40 AGONIST DYNAMICALLY ALTERS DENDRITIC, ENDOTHELIAL AND T CELL SUBSETS WITHIN THE ESTABLISHED TUMOR MICROENVIRONMENT
Little preclinical modeling currently exists to support the use of OX40 agonists as therapeutic agents in the setting of advanced cancers, as well as, the mechanisms through which therapeutic efficacy is achieved. We demonstrate that treatment of mice bearing well-established day 17 sarcomas with a...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058673/ https://ncbi.nlm.nih.gov/pubmed/21045144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1369 |
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