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Science gone translational: the OX40 agonist story
OX40 (CD134) is a tumor necrosis factor (TNF) receptor expressed primarily on activated CD4(+) and CD8(+) T cells and transmits a potent costimulatory signal when engaged. OX40 is transiently expressed after T-cell receptor engagement and is upregulated on the most recently antigen-activated T cells...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622727/ https://ncbi.nlm.nih.gov/pubmed/22017441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2011.01069.x |
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