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Science gone translational: the OX40 agonist story

OX40 (CD134) is a tumor necrosis factor (TNF) receptor expressed primarily on activated CD4(+) and CD8(+) T cells and transmits a potent costimulatory signal when engaged. OX40 is transiently expressed after T-cell receptor engagement and is upregulated on the most recently antigen-activated T cells...

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Main Authors: Weinberg, Andrew D., Morris, Nicholas P., Kovacsovics-Bankowski, Magdalena, Urba, Walter J., Curti, Brendan D.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622727/
https://ncbi.nlm.nih.gov/pubmed/22017441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2011.01069.x
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