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The TNFRs OX40, 4-1BB, and CD40 as targets for cancer immunotherapy

T cell-mediated rejection of tumors requires signals from the T cell receptor and co-stimulatory molecules to license effector functions of tumor-antigen specific T cells. There is also an array of immune suppressive mechanisms within the tumor microenvironment that can suppress anti-tumor immunity....

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Autors principals: Moran, Amy E., Kovacsovics-Bankowski, Magdalena, Weinberg, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815601/
https://ncbi.nlm.nih.gov/pubmed/23414607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.01.004
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