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The TNFRs OX40, 4-1BB, and CD40 as targets for cancer immunotherapy
T cell-mediated rejection of tumors requires signals from the T cell receptor and co-stimulatory molecules to license effector functions of tumor-antigen specific T cells. There is also an array of immune suppressive mechanisms within the tumor microenvironment that can suppress anti-tumor immunity....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3815601/ https://ncbi.nlm.nih.gov/pubmed/23414607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.01.004 |
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