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Biliverdin Inhibits Hepatitis C Virus NS3/4A Protease Activity: Mechanism for the Antiviral Effects of Heme Oxygenase?
Induction of heme oxygenase -1 (HO-1) inhibits hepatitis C virus (HCV) replication. Of the products of the reaction catalyzed by HO-1 iron has been shown to inhibit HCV RNA polymerase, but little is known about the antiviral activity of biliverdin (BV). Herein, we report that BV inhibits viral repli...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058505/ https://ncbi.nlm.nih.gov/pubmed/21105106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23921 |
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