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Metalloprotoporphyrin Inhibition of HCV NS3-4A Protease: Structure–Activity Relationships
BACKGROUND: Antiviral actions of tetrapyrroles have been described in a number of systems. Our goal was to evaluate antagonism of the HCV NS3-4A protease by a variety of common porphyrins and characterize structure–activity relationships that may be useful for future drug design of HCV and related F...
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| Pubblicato in: | Drug Des Devel Ther |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7048954/ https://ncbi.nlm.nih.gov/pubmed/32158194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S201089 |
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