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An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe

There have been several reports describing elevation of oxidized RNA in aging or age-related diseases, however RNA oxidation has been assessed solely based on 8-hydroxy-guanosine levels. In this study, Aldehyde Reactive Probe (ARP), which was originally developed to detect DNA abasic sites was used...

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Hlavní autoři: TANAKA, MIKIEI, SONG, HAN, KÜPFER, PASCAL A., LEUMANN, CHRISTIAN J., SONNTAG, WILLIAM E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058411/
https://ncbi.nlm.nih.gov/pubmed/21062214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2010.535529
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