Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons

Parkinson’s disease is a neurodegenerative disorder characterized by severe motor deficits mainly due to degeneration of dopaminergic neurons in the substantia nigra. Decreased levels of the cell’s most important anti-oxidant, glutathione, have been detected in nigral neurons of Parkinson patients,...

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Hlavní autoři: Garrido, Manuel, Tereshchenko, Yuliya, Zhevtsova, Zinayida, Taschenberger, Grit, Bähr, Mathias, Kügler, Sebastian
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2010
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058355/
https://ncbi.nlm.nih.gov/pubmed/21191602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0791-x
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