A novel Minimalist Cell-Free MHC Class II Antigen Processing System Identifies Immunodominant Epitopes

Immunodominance is defined as restricted responsiveness of T cells to a few selected epitopes from complex antigens. Strategies currently used for elucidating CD4(+) T cell epitopes are inadequate. To understand the mechanism of epitope selection for helper T cells, we established a cell-free antige...

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Autores principales: Hartman, Isamu Z., Kim, AeRyon, Cotter, Robert J., Walter, Kimberly, Dalai, Sarat K., Boronina, Tatiana, Griffith, Wendell, Schwenk, Robert, Lanar, David E., Krzych, Urszula, Cole, Robert N., Sadegh-Nasseri, Scheherazade
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058316/
https://ncbi.nlm.nih.gov/pubmed/21037588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2248
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