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Exocytosis requires asymmetry in the central layer of the SNARE complex

Assembly of SNAREs (soluble N-ethylmaleimide- sensitive factor attachment protein receptors) mediates membrane fusions in all eukaryotic cells. The synaptic SNARE complex is represented by a twisted bundle of four α-helices. Leucine zipper-like layers extend through the length of the complex except...

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Bibliographic Details
Main Authors: Ossig, Rainer, Schmitt, Hans Dieter, de Groot, Bert, Riedel, Dietmar, Keränen, Sirkka, Ronne, Hans, Grubmüller, Helmut, Jahn, Reinhard
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC305815/
https://ncbi.nlm.nih.gov/pubmed/11080147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6000
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