SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

During exocytosis, SNARE proteins of secretory vesicles interact with the corresponding SNARE proteins in the plasmalemma to initiate the fusion reaction. However, it is unknown whether SNAREs are uniformly distributed in the membrane or whether specialized fusion sites exist. Here we report that in...

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Pubblicato in:	EMBO J
Autori principali:	Lang, Thorsten, Bruns, Dieter, Wenzel, Dirk, Riedel, Dietmar, Holroyd, Phillip, Thiele, Christoph, Jahn, Reinhard
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125434/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11331586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.9.2202
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