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SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

During exocytosis, SNARE proteins of secretory vesicles interact with the corresponding SNARE proteins in the plasmalemma to initiate the fusion reaction. However, it is unknown whether SNAREs are uniformly distributed in the membrane or whether specialized fusion sites exist. Here we report that in...

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Détails bibliographiques
Auteurs principaux: Lang, Thorsten, Bruns, Dieter, Wenzel, Dirk, Riedel, Dietmar, Holroyd, Phillip, Thiele, Christoph, Jahn, Reinhard
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC125434/
https://ncbi.nlm.nih.gov/pubmed/11331586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.9.2202
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