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SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

During exocytosis, SNARE proteins of secretory vesicles interact with the corresponding SNARE proteins in the plasmalemma to initiate the fusion reaction. However, it is unknown whether SNAREs are uniformly distributed in the membrane or whether specialized fusion sites exist. Here we report that in...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Lang, Thorsten, Bruns, Dieter, Wenzel, Dirk, Riedel, Dietmar, Holroyd, Phillip, Thiele, Christoph, Jahn, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125434/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11331586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.9.2202
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