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t-SNARE dephosphorylation promotes SNARE assembly and exocytosis in yeast

The role of protein phosphorylation in secretion is not well understood. Here we show that yeast lacking the Snc1,2 v-SNAREs, or bearing a temperature-sensitive mutation in the Sso2 t-SNARE, are rescued at restrictive conditions by the addition of ceramide precursors and analogs to the growth medium...

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Autores principales: Marash, Michael, Gerst, Jeffrey E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC133487/
https://ncbi.nlm.nih.gov/pubmed/11157748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.3.411
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