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Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells

The tumour suppressor p53 and the glucocorticoid receptor (GR) respond to different types of stress. We found that dexamethasone-activated endogenous and exogenous GR inhibit p53-dependent functions, including transactivation, up- (Bax and p21(WAF1/CIP1)) and down- (Bcl2) regulation of endogenous ge...

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Hlavní autoři: Sengupta, Sagar, Vonesch, Jean-Luc, Waltzinger, Caroline, Zheng, Hong, Wasylyk, Bohdan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305812/
https://ncbi.nlm.nih.gov/pubmed/11080152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6051
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