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Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells

The tumour suppressor p53 and the glucocorticoid receptor (GR) respond to different types of stress. We found that dexamethasone-activated endogenous and exogenous GR inhibit p53-dependent functions, including transactivation, up- (Bax and p21(WAF1/CIP1)) and down- (Bcl2) regulation of endogenous ge...

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Autori principali: Sengupta, Sagar, Vonesch, Jean-Luc, Waltzinger, Caroline, Zheng, Hong, Wasylyk, Bohdan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC305812/
https://ncbi.nlm.nih.gov/pubmed/11080152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6051
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