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Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells
The tumour suppressor p53 and the glucocorticoid receptor (GR) respond to different types of stress. We found that dexamethasone-activated endogenous and exogenous GR inhibit p53-dependent functions, including transactivation, up- (Bax and p21(WAF1/CIP1)) and down- (Bcl2) regulation of endogenous ge...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305812/ https://ncbi.nlm.nih.gov/pubmed/11080152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6051 |
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