Unprecedented proximal binding of nitric oxide to heme: implications for guanylate cyclase

Microbial cytochromes c′ contain a 5-coordinate His-ligated heme that forms stable adducts with nitric oxide (NO) and carbon monoxide (CO), but not with dioxygen. We report the 1.95 and 1.35 Å resolution crystal structures of the CO- and NO-bound forms of the reduced protein from Alcaligenes xylosox...

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Pubblicato in:	EMBO J
Autori principali:	Lawson, David M., Stevenson, Clare E.M., Andrew, Colin R., Eady, Robert R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2000
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11060017/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.21.5661
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