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A robust multifactor dimensionality reduction method for detecting gene-gene interactions with application to the genetic analysis of bladder cancer susceptibility

A central goal of human genetics is to identify and characterize susceptibility genes for common complex human diseases. An important challenge in this endeavor is the modeling of gene-gene interaction or epistasis that can result in non-additivity of genetic effects. The multifactor dimensionality...

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Detalhes bibliográficos
Main Authors: Gui, Jiang, Andrew, Angeline S., Andrews, Peter, Nelson, Heather M., Kelsey, Karl T., Karagas, Margaret R., Moore, Jason H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057873/
https://ncbi.nlm.nih.gov/pubmed/21091664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2010.00624.x
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