A Computationally Efficient Hypothesis Testing Method for Epistasis Analysis using Multifactor Dimensionality Reduction

Multifactor dimensionality reduction (MDR) was developed as a nonparametric and model-free data mining method for detecting, characterizing, and interpreting epistasis in the absence of significant main effects in genetic and epidemiologic studies of complex traits such as disease susceptibility. Th...

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Autors principals: Pattin, Kristine A., White, Bill C., Barney, Nate, Gui, Jiang, Nelson, Heather H., Kelsey, Karl R., Andrew, Angeline S., Karagas, Margaret R., Moore, Jason H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700860/
https://ncbi.nlm.nih.gov/pubmed/18671250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20360
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