Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase

Crystal structure analysis of Flavivirus methyltransferases uncovered a flavivirus-conserved cavity located next to the binding site for its cofactor, S-adenosyl-methionine (SAM). Chemical derivatization of S-adenosyl-homocysteine (SAH), the product inhibitor of the methylation reaction, with substi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lim, Siew Pheng, Sonntag, Louis Sebastian, Noble, Christian, Nilar, Shahul H., Ng, Ru Hui, Zou, Gang, Monaghan, Paul, Chung, Ka Yan, Dong, Hongping, Liu, Boping, Bodenreider, Christophe, Lee, Gladys, Ding, Mei, Chan, Wai Ling, Wang, Gang, Jian, Yap Li, Chao, Alexander Theodore, Lescar, Julien, Yin, Zheng, Vedananda, T. R., Keller, Thomas H., Shi, Pei-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057852/
https://ncbi.nlm.nih.gov/pubmed/21147775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.179184
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados