Co-precipitation of Phosphate and Iron Limits Mitochondrial Phosphate Availability in Saccharomyces cerevisiae Lacking the Yeast Frataxin Homologue (YFH1)

Saccharomyces cerevisiae cells lacking the yeast frataxin homologue (Δyfh1) accumulate iron in the mitochondria in the form of nanoparticles of ferric phosphate. The phosphate content of Δyfh1 mitochondria was higher than that of wild-type mitochondria, but the proportion of mitochondrial phosphate...

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Detalhes bibliográficos
Main Authors: Seguin, Alexandra, Santos, Renata, Pain, Debkumar, Dancis, Andrew, Camadro, Jean-Michel, Lesuisse, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057820/
https://ncbi.nlm.nih.gov/pubmed/21189251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163253
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