Turning Saccharomyces cerevisiae into a Frataxin-Independent Organism

Frataxin (Yfh1 in yeast) is a conserved protein and deficiency leads to the neurodegenerative disease Friedreich’s ataxia. Frataxin is a critical protein for Fe-S cluster assembly in mitochondria, interacting with other components of the Fe-S cluster machinery, including cysteine desulfurase Nfs1, I...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Yoon, Heeyong, Knight, Simon A. B., Pandey, Alok, Pain, Jayashree, Turkarslan, Serdar, Pain, Debkumar, Dancis, Andrew
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440810/
https://ncbi.nlm.nih.gov/pubmed/25996596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005135
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