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Turning Saccharomyces cerevisiae into a Frataxin-Independent Organism
Frataxin (Yfh1 in yeast) is a conserved protein and deficiency leads to the neurodegenerative disease Friedreich’s ataxia. Frataxin is a critical protein for Fe-S cluster assembly in mitochondria, interacting with other components of the Fe-S cluster machinery, including cysteine desulfurase Nfs1, I...
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| Pubblicato in: | PLoS Genet |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440810/ https://ncbi.nlm.nih.gov/pubmed/25996596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005135 |
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